Preparation H and puffy eyes


Many of us are familiar with Preparation H for its use in treating hemorrhoids. But did you know that Preparation H is also used to fight wrinkles and relieve puffy eyes?

The ‘secret’ ingredient in Preparation H is Bio-dyne, also known as Live Yeast Cell Derivative – LYCD. This formulation is found only in the Preparation H marketed in Canada and not in the US version. Preparation H Cream found in the USA does not contain biodyne, which was removed when the product was reformulated years ago. Instead, it contains phenylephrine HCI 0.25 % – a vasoconstrictor (shrinks vessels) that some dermatologists claim will constrict capillaries and temporarily reduce dark circles and puffy eyes. However, many individuals report irritation and burning when using the US version of Preparation H.

How does Biodyne work?

There is data to suggest that LYCD accelerates wound healing and is biologically active on skin cells. The active ingredient in biodyne has been isolated as a protein fraction containing a mixture of several peptides. It’s thought that Peptides offer benefits to skin including:

  • Wound healing
  • Certain skin conditions such as atopic dermatitis and eczema.
  • Increasing skin thickness
  • Reducing wrinkle volume

Used by those in the know

Listed in Diane Iron’s popular book “The World’s Best Kept Beauty Secrets”, Irons claims that many middle-aged celebrities use Preparation H to maintain their youthful looks. Some say that supermodels swear by it as a beauty essential. They claim that this hemorrhoid cream gives them an instant lift when eye bags bother them.

Though its bright yellow and plain packaging won’t win any aesthetic awards, if you’ve tried other products and they don’t work, you may want to consider giving reasonably priced Preparation H a try for puffy eyes.�

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Sharmani said,

March 1, 2012 @ 1:03 pm

for Barbara: The gel is not available in Canada, although it sounds lovely. We are able to offer only the cream with BioDyne. Comparing the two products would make an interesting study. Also, the cost is designed to be consistent with that given by other online Canadian pharmacies, but it’s also true that products in general tend to be more expensive in Canada. Having said that, if you were to visit us on vacation and buy directly from a walk-in pharmacy, you’d likely find it less expensive than you will online. Hope this helps! Sharmani

Pam said,

March 8, 2012 @ 4:57 pm

Sharmani, I saw one of your posted which suggests that the cream version is the one to get. When I ordered I didn’t realize I ordered the ointment. Other than it being on the greasy side does it still work as the cream does?

Sharmani said,

March 9, 2012 @ 12:59 pm

For Pam: Actually, we no longer carry the ointment, so if you order Prep H with Biodyne from us, it will certainly be the cream. Both are effective, but the cream is a more acceptable texture for most people. Hope this helps, Sharmani

Brandy said,

March 14, 2012 @ 8:26 pm

Will it work for DRY , RED , IRRITATED EYELIDS ?

Sharmani said,

March 15, 2012 @ 12:14 pm

For Brandy: You want to know if Preparation H with BioDyne is indicated in the case of dry, red, irritated eyelids. I would definitely advise you to see a doctor or dermatologist to verify the cause of this condition before proceeding with any kind of treatment. All the best, Sharmani

Madalyn said,

April 1, 2012 @ 5:03 pm

The U.S. version worked just great after oral surgery some years ago. Bruises and swelling and all disappeared quickly. I am ready to try it again due to an accident that bruised my face.

Sharmani said,

April 2, 2012 @ 1:37 pm

Madalyn, Thanks for the tip! Preparation H acts as a vasoconstrictor, so the same action which treats hemorrhoids will likely decrease bruising and swelling. Here’s to a speedy recovery after your injury. Sharmani

Sharmani said,

April 2, 2012 @ 1:41 pm

Hello Vanella, using Prep H to treat skin after waxing is not a use of the product which is known to me or indicated for the product. In fact, it’ s possible that irritated skin will not respond well to the use of Preparation H. We never recommend it for itchy conditions or any sensitive, dry or flaking area either. However, it appears to decrease swelling, puffiness and sagging skin. If you want to explore further, I’d recommend consulting your esthetician or dermatologist. Best wishes, Sharmani

lesley said,

June 17, 2012 @ 6:53 am

I bought some prep h cream from canada online, can’t remember where. But today I used it on my forehead wrinkles. Yes the product smells but if you can bear that it was amazing! Straightaway after I rubbed it in I noticed a slight difference the grooves where not so deep from tiredness. Straight after I actually could feel that my skin area where I had applied felt tightened and continued to feel tightened. I will post results after using for a few days. I have not been able to bring myself to use it all over my face yet due to the smell nor would I use it everyday but if you have an event or something coming up its definitely useful for that! I’m going visiting relatives so will be nice to go looking refreshed a bit.

Shari Gauthier said,

December 5, 2012 @ 10:30 am

Hi everyone,
I am from Canada and I have been using Prep H the creme for about a year now and have seen wonderful results. Skin has tightened up around my eyes, forhead and mouth. I use it once at bedtime and if my eyes are a little puffy in the morning I will put some on. It does smell fishy at first but as you use it more and more the smell seems to not affect you and you get use to it. It is a very inexpensive way to help your skin look fresher and a tube can last up to two months of use. I am 43 years old and people think that I am 33 instead. I didn’t use it for one month one time because the store that I was getting it at couldn’t get any, there was a shortage of supplies at the warehouse I was told. “Guess what happened,” wrinkles started to come back, was I glad when they called and said the shipment had come in. Now everything is back to normal and I buy two tubes at a time in order not to run out. I have no side effects, my skin is tight and fresh even after use for one year. Well good luck people and I hope you have the same results that I have incurred.

Amanda said,

January 22, 2013 @ 12:36 pm

Hi I’m all the way in London and I’ve only just heard about this amazing cream.
Obviously we can’t buy the original formula either but, I found somewhere that sells the ointment! It has biodyne in it so I’m hoping it works as well as the cream?
I would be very grateful for some feedback? Ointment v Cream!

Many thanks

Sharmani said,

January 25, 2013 @ 1:27 pm

For Amanda:
The full ingredient list for Preparation H cream is available on our website and can be used to compare the active ingredients of the ointment version you have in London. As for choosing the cream or ointment, it is a matter of which form you personally prefer.
Best, Sharmani

Cynthia said,

January 25, 2013 @ 1:36 pm

I use it after I take a shower. Its the first thing that goes on my face. Meanwhile I’ll get dressed and what not. Then i just put my usual face cream over it, then the makeup. I don’t wash it off. I noticed real results in about two weeks. I love it! I also use it on my neck top of my hands and my thighs.

Tammy said,

August 5, 2013 @ 5:50 pm

I would like to know if this would be helpful in tightening my neck area!

Sharmani said,

August 6, 2013 @ 1:58 pm

For Tammy:
Although BioDyne contains several peptides that are useful in skincare for boosting collagen production and reducing the appearance of wrinkles, no clinical studies have been done on the effectiveness of tightening the neck area. In addtion to increasing collagen production and protecting your skin against the sun, you may want to consider adding a firming cream to your skincare routine. Be warned, however, that there is no quick fix.
Best, Sharmani

Jessie said,

February 18, 2014 @ 8:04 pm

Hi, I’m wondering why the Dermatologists and Cosmetic companies aren’t all over this information. I mean, if it’s true, wouldn’t they make a lot of money off of products that actually work?

Sharmani said,

February 19, 2014 @ 11:48 am

For Jessie,
No clinical studies have been done specifically on the effectiveness of Preparation H Cream for puffy eyes and wrinkles. However, since BioDyne is a peptide which functions by boosting collagen production, anecdotal evidence indicates that it works on fine lines and wrinkles. Peptides, with their moisture-binding and cell-communicating abilities, can be found in many effective anti-aging skin care products.
Best, Sharmani

janice32 said,

April 24, 2014 @ 3:26 pm

ok, I’m almost afraid to say this because I don’t want the price to get jacked up (seriously!) – but I used Prep H for many years – and it does work! BUT, I stopped using the Prep H for the Made from Earth Cucumber Cooling Gel. This is the best thing (next to preparation H) that I’ve found for my under eyes.It is a gel and it does shrink the under eye eggs and just really smoothes and tightens it out pretty well (for me). I have fairly bad under eyes, so I have been well pleased with this.

Jo-Ann Brennan said,

August 20, 2015 @ 7:02 am

But if you don’t purchase the Canadian proper PH does the American made proper PH have the same effects?

Sharmani said,

August 26, 2015 @ 10:39 am

For Jo-Ann,
BioDyne, the active ingredient in the Canadian formula of Preparation H, contains several peptides, which are widely used in anti-wrinkle and anti-aging creams. As far as we know, the American formula, which does not contain BioDyne, would not have the same effect on wrinkles and puffiness under the eyes.
Best, Sharmani

Lynn said,

November 11, 2015 @ 8:44 pm

Do you still sell the Canadian Preparation H on your site? I can’t find it

Sharmani said,

November 12, 2015 @ 11:29 am

For Lynn,
Yes, we still carry Preparation H Cream with BioDyne. Follow the link here to our webpage.
Best, Sharmani

sue said,

April 7, 2016 @ 12:27 pm

Hi I have heard that the original prep h could thin the skin. Does the Prep H with biodyne also thin the skin or not? Thanks Suzie

Sharmani said,

April 14, 2016 @ 1:12 pm

For Sue,
Thanks for your question. The Canadian version of Preparation H with BioDyne does not contain any ingredients that are known to thin the skin. However, if this is a particular concern to you that is connected to an existing condition, you may want to consult your health care professional prior to use.
Best, Sharmani

Henrine Parker said,

April 15, 2016 @ 7:28 pm

I started using the Canadian preparation H about a month ago for sagging skin under may neck. I use it basically as a night cream. Thus far, I have noticed a very pleasant improvement! Will the sagging return if I stop using the preparation H? I am also doing facial exercises.

Sharmani said,

April 18, 2016 @ 9:53 am

For Henrine,
Thank you for your question. We are pleased to hear that the Preparation H Cream with BioDyne is working for you. It’s a customer favorite here! Although skin reacts very individually, in general, maintenance is usually required to keep up the results when it comes to healthy skin. Permanent results with no maintenance often involve more invasive procedures.
Best, Sharmani

Kim said,

November 24, 2016 @ 1:22 pm

For Sue – There IS a formulation of Preparation H that will thin the skin, but it is not these. The type of Preparation H that will cause thinning of the skin is the one that contains Hydrocortisone 1%, and it is clearly labeled right underneath Preparation H. Don’t buy that one. It is common knowledge that longer term use of Hydrocortisone will thin your skin, but it is used on some skin problems that need some extra help – for a limited period of time. Anyway, you needn’t worry about getting the wrong one as the label clearly shows whether it has Hydrocortisone or not – right on the box in the front in big letters.

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